Installing Extras

This chapter gives technical information on how to install the VarFish extra services. These are:

Jannovar REST Service (strongly recommended)

molecular impact prediction for all affected transcripts

Exomiser REST Service

required for phenotype-prioritization of variants using the Exomiser.

CADD Annotation Service

required for variant pathogenicity annotation with CADD scores. NB: this depends on CADD-scripts which is only free for non-commercial use (see license).

The audience of this chapter are those who want to install VarFish on their own infrastructure.

Jannovar REST Service

TODO

Exomiser REST Service

TODO

CADD REST Service

TODO